Malassezia globosa

^[1]

Pathology

Malassezia (especially, M globosa) travel from the gut through the sphincter of Oddi to the pancreas
- in pancreatic cancer, M globosa is present in concentrations 3000 X its concentrations in normal or benignly inflamed pancreatic tissue^[1]
- Malassezia triggered tumor growth involves inflammation via activation of complement C3^[1]
M globosa is a cause of dandruff^[1]

↑ ^1.0 ^1.1 ^1.2 ^1.3 Aykut B et al. The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL. Nature 2019 Oct; 574:264 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31578522 https://www.nature.com/articles/s41586-019-1608-2