cefiderocol (Fetroja)

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Introduction

FDA-approved Nov 2019

Indications

Antimicrobial activity

Mechanism of action

More general terms

References

  1. 1.0 1.1 Business Wire. Oct 16, 2019 U.S. FDA Advisory Committee Recommends Approval of Cefiderocol for Treatment of Complicated Urinary Tract Infections. https://www.businesswire.com/news/home/20191016005916/en/U.S.-FDA-Advisory-Committee-Recommends-Approval-Cefiderocol
  2. 2.0 2.1 2.2 Dobias J, Denervaud-Tendon V, Poirel L, Nordmann P. Activity of the novel siderophore cephalosporin cefiderocol against multidrug-resistant Gram-negative pathogens. Eur J Clin Microbiol Infect Dis. 2017 Dec;36(12):2319-2327. PMID: https://www.ncbi.nlm.nih.gov/pubmed/28748397 https://link.springer.com/article/10.1007%2Fs10096-017-3063-z
  3. 3.0 3.1 Brooks M FDA OKs New Antibacterial Cefiderocol (Fetroja) for Complicated UTI. Medscape. Nov 15, 2019. https://www.medscape.com/viewarticle/921401
    FDA NEWS RELEASE. Nov 14, 2019 FDA approves new antibacterial drug to treat complicated urinary tract infections as part of ongoing efforts to address antimicrobial resistance. https://www.fda.gov/news-events/press-announcements/fda-approves-new-antibacterial-drug-treat-complicated-urinary-tract-infections-part-ongoing-efforts
  4. 4.0 4.1 4.2 Susman E Novel Siderophore Cephalosporin Nets Promising Results in Tough-to-Treat CRAB. PROVE offers real-world data in carbapenem-resistant Acinetobacter baumannii. MedPage Today October 23, 2022 https://www.medpagetoday.com/meetingcoverage/idweek/101369
  5. 5.0 5.1 Rapid Review Quiz: Hospital-Acquired Pneumonia Medscape. Sept 15, 2022 https://reference.medscape.com/viewarticle/980567