Lidocaine subcutaneous

Indications

• local anesthetic
• lidocaine dripped on skin before subcutaneous lidocaine injections reduces pain of procedures

Dosage

Local anesthetic: 0.5%, 1%, 1.5%, 2%, 4%, 10%, 20%. with epinephrine 0.5%, 1%, 1.5%, 2%.

Mechanism of action

local anesthetic

• amide-type local anesthetic
• reversible blocks nerve conduction in all nerve fibers (sensory, motor, autonomic) by decreasing permeability of nerve to Na+
• decreases rate of nerve depolarization
• increases threshold of excitability
• prevents propagation of action potential
• autonomic activity is lost 1st followed by sensory & motor function

More general terms

• lidocaine (Xylocaine)
• local anesthetic