plazomicin (Zemdri)

^[1]^[2]

Indications

* trial of plazomicin vs colistin bloodstream infections or nosocomial pneumonia caused by carbapenem-resistant Enterobacteriaceae stopped early because of slow recruitment, limiting conclusions^[2]

↑ Reuters Staff FDA Approves Plazomicin (Zemdri) for Urinary Tract Infections. Medscape - Jun 26, 2018 https://www.medscape.com/viewarticle/898542
↑ ^2.0 ^2.1 Wagenlehner FME, Cloutier DJ, Komirenko AS et al Once-Daily Plazomicin for Complicated Urinary Tract Infections. N Engl J Med 2019; 380:729-740. Feb 21, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30786187 https://www.nejm.org/doi/full/10.1056/NEJMoa1801467
McKinnell JA et al Plazomicin for Infections Caused by Carbapenem-Resistant Enterobacteriaceae. N Engl J Med 2019; 380:791-793. Feb 21, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30786196 https://www.nejm.org/doi/full/10.1056/NEJMc1807634
Cox E, Nambiar S, Baden L. Needed: Antimicrobial Development N Engl J Med 2019; 380:783-785. Feb 21, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30786194 https://www.nejm.org/doi/full/10.1056/NEJMe1901525