Proquad (measles, mumps, rubella [MMR] plus varicella viruses live, MMRV)

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Indications

  • immunization of children 4-12* years of age
  • may be used if 2nd dose of MMR is to be administered

Contraindications

  • infants 1-2 years of age*

Adverse effects

* CDC recommends that MMR vaccine be given separate from varicella vaccine at 1-2 years of age due to risk of febrile seizures

* at 4-6 years of age the risk of febrile seizures has resolved[4]

Mechanism of action

More general terms

Additional terms

References

  1. Monthly Prescribing Reference http://www.PrescribingReference.com
  2. Shinefield H et al, Evaluation of quadrivalent measles, mumps, rubella and varicella vaccine in healthy children Pediatric Infect Dis J 2005; 24:665 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16094217
  3. 3.0 3.1 Marin M, Broder KR, Temte JL, Snider DE, Seward JF, Centers for Disease Control and Prevention (CDC). Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2010 May 7;59(RR-3):1-12. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20448530 corresponding NGC guideline withdrawn Jan 2016
  4. 4.0 4.1 Klein NP et al Measles-Containing Vaccines and Febrile Seizures in Children Age 4 to 6 Years Pediatrics April 2, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22473362 <Internet> http://pediatrics.aappublications.org/content/early/2012/03/28/peds.2011-3198.abstract