semaxinib (SU5416)

Dosage

• BID

Mechanism of action

• targets VEGFR 1-3, also PDGFR, c-kit, Flt-3

Clinical trials

phase 3 trials, disappointing results

More general terms

• small inhibitory antineoplastic agent (ib drug)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=123015
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5329098