dioxin poisoning

Etiology

• exposure to dioxin

Clinical manifestations

• chloracne, large monomorphic comedones (cysts)
• may evolve into severe inflammatory scarring lesions

Laboratory

• dioxin in air
• dioxin in water
• dioxin in serum/plasma
• liver function tests
• complete blood count
• coagulation studies

Management

• remove from offending agent
• chloracne is resistant to treatment

Additional terms

• 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin TCDD)
• agent orange