lifitegrast (Xiidra)

Indications

• dry eyes (xerophthalmia)

Dosage

• 1 drop OU BID (~ q12 hours)
• Xiidr (lifitegrast ophthalmic solution) 5%

Adverse effects

• eye irritation, discomfort or blurred vision
• dysgeusia

Mechanism of action

• LFA-1 antagonist

More general terms

• lymphocyte function-associated antigen 1 (LFA-1) antagonist
• ophthalmic agent (eyedrops)

Additional terms

• lymphocyte function-associated antigen-1 (LFA-1, leukocyte adhesion protein LFA-1, integrin alpha-L/beta-2, CD11a/CD18)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=11965427
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=56963348