scalp cooling system; cooling cap (DigniCap)
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Indications
- reduction of chemotherapy (taxane)-related alopecia in women treated for breast cancer[1][2]
Procedure
- cooling device is a two-cap system:
- an inner silicon cap circulates a refrigerated fluid
- an outer neoprene cap acts as an insulator
- device worn during chemotherapy, 30 minutes before & 90 minutes afterward[2]
Mechanism of action
- lowers temperature of scalp
- diminishes blood flow to the scalp
- reduces amount of chemotherapy reaching hair follicles[2]
* preserves hair in 50% of women
Notes
- cost of $1500-3000/patient (2017)[3]
More general terms
References
- ↑ 1.0 1.1 Dignitana Brings First and Only U.S. FDA-Cleared Scalp Cooling System to Market. DigniCap. Dec 8, 2015 http://www.dignicap.com/dignitana-fda-clearance/
- ↑ 2.0 2.1 2.2 2.3 Orciari Herman A, Sadoughi S, Sofair A Scalp-Cooling Device Limits Hair Loss from Chemotherapy. Physician's First Watch, Dec 12, 2016 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
Huseman A Scalp-cooling device cuts hair loss in breast cancer patients undergoing chemotherapy. Baylor College of Medicine News Release. Dec 9, 2016 https://www.bcm.edu/news/cancer/scalp-cooling-reduces-chemotherap-hair-loss - ↑ 3.0 3.1 Nangia J, Wang T, Osborne C et al Effect of a Scalp Cooling Device on Alopecia in Women Undergoing Chemotherapy for Breast Cancer: The SCALP Randomized Clinical Trial. JAMA. 2017 Feb 14;317(6):596-605. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28196254 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2601500
Rugo HS, Klein P, Melin SA et al Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer. JAMA. 2017 Feb 14;317(6):606-614. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28196257 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2601503
Hershman DL. Scalp Cooling to Prevent Chemotherapy-Induced Alopecia: The Time Has Come. JAMA. 2017 Feb 14;317(6):587-588. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28196237 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2601483