drug adverse effects of cephalosporins
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Adverse effects
- Stevens-Johnson syndrome
- erythema multiforme
- toxic epidermal necrolysis
- renal dysfunction
- toxic nephropathy
- aplastic anemia
- hemolytic anemia
- hemorrhage
- cholestasis
- pancytopenia
- seizures[2]
- cephalosporin allergy uncommon[3]
- patients with allergy to one cephalosporin can often tolerate others[4]
- acute generalized exanthematous pustulosis[5]
More general terms
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- ↑ 2.0 2.1 Medications Can Cause Seizures Prescriber's Letter 10(3):16 2003 Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=190320&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 3.0 3.1 Macy E, Contreras R. Adverse reactions associated with oral and parenteral use of cephalosporins: A retrospective population-based analysis. J Allergy Clin Immunol 2015 Mar; 135:745 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25262461 <Internet> http://www.jacionline.org/article/S0091-6749%2814%2901193-2/abstract
- ↑ 4.0 4.1 Romano A et al. IgE-mediated hypersensitivity to cephalosporins: Cross-reactivity and tolerability of alternative cephalosporins. J Allergy Clin Immunol 2015 Sep; 136:685 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25930196 <Internet> http://www.jacionline.org/article/S0091-6749%2815%2900410-8/abstract
- ↑ 5.0 5.1 Aday AW et al CLINICAL PROBLEM-SOLVING. Prevention as Precipitant. N Engl J Med 2016; 375:471-475. August 4, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27518666 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMcps1301580