Bacillus subtilis
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Introduction
found in soil and the gastrointestinal tract of ruminants and humans
Indications
- probiotic
- 30 days of Bacillus subtilis eliminates 97% of Staphylococcus aureus in the gut
- affects colonizsation of Staphylococcus aureus in the nose
Dosage
- 240 mg once a day
Capsules: 60 mg
Laboratory
- Gram-positive, catalase-positive bacterium
- facultative aerobe
- Bacillus subtilis IgE in serum
Mechanism of action
- does not kill Staphylococcus aureus, but diminishes its ability to colonize
More general terms
Component of
References
- ↑ Wikipedia: Bacillus subtilis https://en.wikipedia.org/wiki/Bacillus_subtilis
- ↑ Kunst F, Ogasawara N, Moszer I et al The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature. 1997 Nov 20;390(6657):249-56. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/9384377 <Internet> http://www.nature.com/nature/journal/v390/n6657/full/390249a0.html
- ↑ Hein I Probiotic Proves Its Might for Staph Decolonization. Bacillus subtilis eliminated most S. aureus in the gut, and without harming microbiome. MedPage Today January 19, 2023 https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/102709
Piewngam P, Khongthong S, Roekngam N Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand: a phase 2, double-blind, randomised, placebo-controlled trial. Lancet Microbe. 2023 Jan 13:S2666-5247(22)00322-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36646104 https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00322-6/fulltext