CYP2C19 genotyping; CYP2C19 allele testing
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Indications
- predicting efficacy of clopidogrel (maybe)
Specimen
- buccal swabs
- blood: 5-10 cc whole blood lavender-top EDTA or Yellow-top ACD-A tubes
Interpretation
- turnaround time: 10 days (5 days for STAT tests)
More general terms
More specific terms
Component of
References
- ↑ Cytochrome P450 2C19 Genotyping Genelex http://www.healthanddna.com/healthcare-professional/p450-2c19-genotyping.html
- ↑ Bauer T et al. Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: Systematic review and meta-analysis. BMJ 2011 Aug 4; 343:d4588 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21816733
- ↑ Holmes MV et al. CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: A systematic review and meta-analysis. JAMA 2011 Dec 28; 306:2704. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22203539
Nissen SE. Pharmacogenomics and clopidogrel: Irrational exuberance? JAMA 2011 Dec 28; 306:2727. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22203545 - ↑ CYP2C19 Allele 2 Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0051104.jsp