disease interaction(s) of diabetes mellitus with hypertension
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Management
- treatment of chronic hypertension
- ACE inhibitors agents of choice
- only ACE inhibitors prevent doubling of serum creatinine
- outcomes with ARB not inferior to ACE inhibitor
- combination of ACE inhibitor plus calcium channel blocker most likely to reduce mortality
- beta-blockers increase mortality
- target systolic blood pressure < 140 mm Hg
- lower target systolic blood pressure associated with higher cardiovascular mortality
- taking antihypertensives at night may prevent failure of nocturnal blood pressure decline in a subset of patients[3]
- ACE inhibitors agents of choice
More general terms
References
- ↑ Wu HY, Huang JW, Lin HJ et al Comparative effectiveness of renin-angiotensin system blockers and other antihypertensive drugs in patients with diabetes: systematic review and bayesian network meta-analysis. BMJ 2013;347:f6008 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24157497 <Internet> http://www.bmj.com/content/347/bmj.f6008
- ↑ Young K, Sadoughi S, Saitz R Antihypertensives in Diabetes Patients with BPs <140 Tied to Higher CV Mortality. Physician's First Watch, Feb 25, 2016 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
Brunstrom M, Carlberg B Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses. BMJ 2016;352:i717 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26920333 Free Article <Internet> http://www.bmj.com/content/352/bmj.i717 - ↑ 3.0 3.1 Lou N More Evidence for Taking Blood Pressure Meds Before Bed? Circadian BP patterns linked to long-term survival in people with diabetes. MedPage Today September 29, 2021. https://www.medpagetoday.com/meetingcoverage/ash/94768