sebelipase alfa (Kanuma)

Indications

• lysosomal acid lipase deficiency

Adverse effects

• nausea/vomiting, diarrhea, constipation
• rhinitis, cough
• fever
• anemia
• headache

Mechanism of action

• recombinant form of the human lysosomal acid lipase produced in the egg whites of genetically engineered chickens

More general terms

• recombinant protein; chimer
• metabolic agent (metabolic modifier)