endothelin receptor antagonist

Introduction

see ambrisentan

Indications

• treatment of pulmonary hypertension

Mechanism of action

• inhibits endothelin receptor
• vasodilator

More general terms

• receptor antagonist
• vasodilator agent

More specific terms

• ambrisentan (Letairis, Volibris)
• aprocitentan (Tryvio)
• bosentan (Tracleer)
• macitentan (Opsumit)
• sparsentan (Filspari)
• tezosentan

Additional terms

• endothelin
• endothelin receptor