proton therapy

^[1]^[2]^[3]^[4]^[5]^[6]

Indications

treatment of cancers susceptible to radiation therapy
- bladder cancer
- breast cancer
- CNS neoplasm
  - brain neoplasms
- gastrointestinal cancer
  - colorectal cancer
- head & neck cancer^[6]
- lung cancer
  - proton therapy as effective as conventional radiotherapy but no less toxic^[2]^[4]
  - early NSCLC located too close to vital organs for conventional treatment may be amenable to proton beam therapy^[3]
- lymphoma
- prostate cancer
- sarcomas
- testicular cancer

More general terms

radiation therapy (XRT)

More specific terms

Flash radiotherapy

References

↑ SCripps Proton Therapy for Cancer Treatment http://campaigns.scripps.org/services/cancer-care__proton-therapy/conditions-treated
↑ ^2.0 ^2.1 Mulcahy N Finally, RCT Results for Proton Therapy in a Cancer. Medscape. Jun 21, 2016. http://www.medscape.com/viewarticle/865137
↑ ^3.0 ^3.1 Susman E Meeting Coverage. RSNA: Protons Destroy Centrally Located Lung Cancer - Early NSCLC close to vital organs found amenable to proton beam approach. MedPage Today. December 03, 2016 http://www.medpagetoday.com/MeetingCoverage/RSNA/61833
↑ ^4.0 ^4.1 Liao Z, Lee JJ, Komaki R et al Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer. J Clin Oncol. 2018 Jan 2:JCO2017740720. [Epub ahead of print] PMID: https://www.ncbi.nlm.nih.gov/pubmed/29293386
↑ Lawrence L Study: Proton Beam as Effective, Less Toxic Than Standard RT.
But limitations make findings less than definitive. MedPage Today. Dec27, 2019 https://www.medpagetoday.com/radiology/therapeuticradiology/84115
Baumann BC, Mitra N, Harton JG et al Comparative Effectiveness of Proton vs Photon Therapy as Part of Concurrent Chemoradiotherapy for Locally Advanced Cancer. JAMA Oncol. Published online Dec 26, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31876914 https://jamanetwork.com/journals/jamaoncology/article-abstract/2757520
↑ ^6.0 ^6.1 Harrison P Proton Beam and Gabapentin Improve Care in Head and Neck Cancer. Medscape - Nov 06, 2020. https://www.medscape.com/viewarticle/940489

[ref1-1] SCripps Proton Therapy for Cancer Treatment http://campaigns.scripps.org/services/cancer-care__proton-therapy/conditions-treated

[ref2-2] 2.0 ^2.1 Mulcahy N Finally, RCT Results for Proton Therapy in a Cancer. Medscape. Jun 21, 2016. http://www.medscape.com/viewarticle/865137

[ref3-3] 3.0 ^3.1 Susman E Meeting Coverage. RSNA: Protons Destroy Centrally Located Lung Cancer - Early NSCLC close to vital organs found amenable to proton beam approach. MedPage Today. December 03, 2016 http://www.medpagetoday.com/MeetingCoverage/RSNA/61833

[ref4-4] 4.0 ^4.1 Liao Z, Lee JJ, Komaki R et al Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer. J Clin Oncol. 2018 Jan 2:JCO2017740720. [Epub ahead of print] PMID: https://www.ncbi.nlm.nih.gov/pubmed/29293386

[ref5-5] Lawrence L Study: Proton Beam as Effective, Less Toxic Than Standard RT.
But limitations make findings less than definitive. MedPage Today. Dec27, 2019 https://www.medpagetoday.com/radiology/therapeuticradiology/84115
Baumann BC, Mitra N, Harton JG et al Comparative Effectiveness of Proton vs Photon Therapy as Part of Concurrent Chemoradiotherapy for Locally Advanced Cancer. JAMA Oncol. Published online Dec 26, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31876914 https://jamanetwork.com/journals/jamaoncology/article-abstract/2757520

[ref6-6] 6.0 ^6.1 Harrison P Proton Beam and Gabapentin Improve Care in Head and Neck Cancer. Medscape - Nov 06, 2020. https://www.medscape.com/viewarticle/940489

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proton therapy

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