transient familial neonatal hyperbilirubinemia

Pathology

• one or more components in the milk may trigger the jaundice in infants who have such mutations

Genetics

• associated with defects in UGT1A1 gene
• mutations are identical to those detected in patients with Gilbert syndrome

Clinical manifestations

• hyperbilirubinemia may lead to jaundice
• breast milk jaundice is a common problem in nursing infants
• may result in prolonged unconjugated hyperbilirubinemia associated with breast milk

More general terms

• genetic disease

Database

• OMIM: https://mirror.omim.org/entry/237900