Cryptococcus neoformans antibody in body fluid

Indications

• evaluation of fungal infection with Cryptococcus neoformans

Clinical significance

• cryptococcal serum antibody titers
  • screening tool
  • serum titer has no prognostic significance
• serologic testing for polysaccharide antigen
  • serum (titer has no prognostic value)
  • cerebrospinal fluid (CSF)
    • positive in 90% of CNS infections
    • titer > 1:1024
      • associated with poor prognosis
      • suggests relapse or treatment failure

More general terms

• Cryptococcus antibody in body fluid

Additional terms

• Cryptococcus neoformans