disease interaction(s) of obstructive sleep apnea (OSA) with insomnia

^[1]^[2]^[3]^[4]

Introduction

Interactions:

obstructive sleep apnea is a major cardiovascular risk factor
- concurrent insomnia does not appear to add to this risk^[3]

ramelteon improves objective but not subjective sleep onset latency in patients with OSA on CPAP^[2]
cognitive behavior therapy is effective in patients with insomnia & obstructive sleep apnea ^[1]

↑ ^1.0 ^1.1 Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022
↑ ^2.0 ^2.1 Gooneratne NS1, Gehrman P, Gurubhagavatula I et al Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea: a randomized placebo- controlled pilot study. J Clin Sleep Med. 2010 Dec 15;6(6):572-80. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21206546
↑ ^3.0 ^3.1 Luyster FS, Kip KE, Buysse DJ et al Traditional and nontraditional cardiovascular risk factors in comorbid insomnia and sleep apnea. Sleep. 2014 Mar 1;37(3):593-600. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24587583
↑ ^4.0 ^4.1 Luyster FS, Buysse DJ, Strollo PJ Jr. Comorbid insomnia and obstructive sleep apnea: challenges for clinical practice and research. J Clin Sleep Med. 2010 Apr 15;6(2):196-204. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20411700