chromosomal instability

Introduction

Instability in VNTR? Originally developed to identify loss of heterozygosity. Microsatellite instability may occur as a result of dysfunction of DNA mismatch repair.

More specific terms

• loss of heterozygosity
• microsatellite instability

Additional terms

• chromosomal aberration
• DNA mismatch repair; post-replication repair; DNA loop repair
• microsatellite or variable number of tandem repeat (VNTR)