sublingual grass pollen extract (Oralair)

Introduction

Also see sublingual immunotherapy

Indications

• first sublingual allergen extract approved for treatment of allergic rhinitis & allergic conjunctivitis due to grass pollen for patients age 10-65 years

Dosage

• sublingual once daily tablet
• observe first dose in clinician's office

Adverse effects

• most common
  • itching & swelling in the mouth
  • throat irritation
• serious: anaphylaxis (boxed warning)

Mechanism of action

• antigen sensitization
  • mix of five grass pollens:
    • Kentucky Blue Grass
    • Orchard Grass
    • Perennial Rye Grass
    • Sweet Vernal Grass
    • Timothy grass

More general terms

• sublingual allergen extract

Additional terms

• sublingual immunotherapy (SLIT)