SERPINE1 gene mutation
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Clinical significance
- defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency*
* heterozygousity of null SERPINE1 allele associated with longevity[2]
More general terms
Additional terms
References
- ↑ Loinc
- ↑ 2.0 2.1 Khan SS, Shah SJ, Klyachko E et al A null mutation in SERPINE1 protects against biological aging in humans. Science Advances. 15 Nov 2017:Vol. 3, no. 11, eaao1617 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29152572 Free PMC Article <Internet> http://advances.sciencemag.org/content/3/11/eaao1617.full