mitochondrial ribosome-associated GTPase 2; GTP-binding protein 5; protein obg homolog 1; ObgH1 (MTG2, GTPBP5, OBGH1)

Function

• role in the regulation of the mitochondrial ribosome assembly & of translational activity
• displays GTPase activity
• involved in the ribosome maturation process
• associates with the mitochondrial ribosome large subunit (GTP-dependent)

Structure

• belongs to the GTP1/OBG family
• contains 1 G (guanine nucleotide-binding) domain

Compartment

• mitochondrial inner membrane
• peripheral membrane protein; matrix side

More general terms

• guanine nucleotide regulatory protein (GNRP)
• guanosine triphosphatase (GTPase)
• mitochondrial membrane protein

Additional terms

• interferon-induced guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; guanine nucleotide-binding protein 5 (GBP5)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26164
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26164
• OMIM: https://mirror.omim.org/entry/610919
• UniProt: http://www.uniprot.org/uniprot/Q9H4K7.html