embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; ES cell-specific 5hmC-binding protein; peptidase SRAPD1; SRAP domain-containing protein 1 (HMCES, C3orf37, DC12, SRAPD1)

Function

• specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (putative)
• may act as a peptidase

Structure

• belongs to the SOS response-associated peptidase family

More general terms

• peptidase; peptide hydrolase
• DNA-binding protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56941
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:56941
• UniProt: http://www.uniprot.org/uniprot/Q96FZ2.html