son of sevenless homolog protein (SOS)

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Introduction

A ras guanine nucleotide exchange factor.

More general terms

More specific terms

References

  1. Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 1993 May 6;363(6424):45-51. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8479536
  2. McCormick F. Signal transduction. How receptors turn Ras on. Nature. 1993 May 6;363(6424):15-6. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8479530
  3. Chardin P, Camonis JH, Gale NW, van Aelst L, Schlessinger J, Wigler MH, Bar-Sagi D. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science. 1993 May 28;260(5112):1338-43. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8493579