IFN-alpha 2b/ribavirin (Rebetron)

Introduction

Combination of ribavirin & interferon alpha-2b.

Indications

• hepatitis C with compensated liver disease

Dosage

interferon alpha-2b: 3 million units SC TID

ribavrin: 1000-1200 mg QD

Adverse effects

• anemia, leukopenia, nausea, anorexia, hyperbilirubinemia more common than with interferon alpha-2b alone

More general terms

• antiviral combination

Components

• interferon [IFN]-alfa 2b (Intron A)
• ribavirin (Virazole, Rebetol, Copegus)