atorvastatin/ezetimibe (Liptruzet)
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Indications
Contraindications
- combination has not been shown to improve cardiovascular outcomes better than atorvastatin alone
Dosage
- 10 mg ezetimibe, 10-80 mg atorvastatin
Adverse effects
- changes in liver function tests
- muscle pain
- memory loss
- tendon problems
Mechanism of action
- Liptruzet 10/20 lowers LDL cholesterol by 53%[1]
- atorvastatin inhibits HMG CoA reductase
- ezetimibe inhibits intestinal absorbtion of cholesterol
- see atorvastatin & ezetimibe
More general terms
Components
References
- ↑ 1.0 1.1 Physician's First Watch, May 6, 2013 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
FDA Approves Merck's LIPTRUZET (ezetimibe and atorvastatin), a New Product That Can Help Powerfully Lower LDL Cholesterol http://www.mercknewsroom.com/press-release/fda-approves-mercks-liptruzet-ezetimibe-and-atorvastatin-new-product-can-help-powerful
Patient Information LIPTRUZETTM (LIP-true-zett) (ezetimibe and atorvastatin) Tablets. http://www.merck.com/product/usa/pi_circulars/l/liptruzet/liptruzet_ppi.pdf