amyotrophic lateral sclerosis type 17
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Introduction
also see amyotrophic lateral sclerosis
Genetics
- associated with defects in CHMP2B
Clinical manifestations
- adult-onset progressive neurodegenerative disorder
- predominantly lower motor neuron involvement
- muscle weakness & wasting of the upper & lower limbs
- bulbar signs
- respiratory insufficiency
More general terms
- amyotrophic lateral sclerosis (ALS); Lou Gerig's disease
- genetic disease of the central nervous system