pancreatic adenocarcinoma genotyping
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Genetics
- associated genetic aberrations:
- ras proto-oncogene
- p53 gene
- germline testing for BRCA, PALB2, ATM, CHEK2, Lynch syndrome
Indications
Specimen
- tumor tissue
- paraffin-embedded tissue
- store fresh tissue at 4 degrees C for 24 hours
- store tissue at -20 degrees C or below
More general terms
Additional terms
References
- ↑ Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025
Shindo K, Yu J, Suenaga M, et al. Deleterious germline mutations in patients with apparently sporadic pancreatic adenocarcinoma. J Clin Oncol. 2017;35:3382-90. PMID: https://www.ncbi.nlm.nih.gov/pubmed/28767289