ficolin-3 deficiency

Genetics

• associated with defects in ficolin-3

Clinical manifestations

• immunodeficiency
• recurrent infections
• brain abscesses
• recurrent warts on the fingers

Laboratory

• lymphocyte count is normal
• serum immunoglobulins are norml
• normal T-cell responses
• selective deficient antibody response to pneumococcal polysaccharide vaccine

More general terms

• enzyme deficiency
• genetic disease of the immune system

Database

• OMIM: https://mirror.omim.org/entry/613860