DNA dC->U-editing enzyme APOBEC-2; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 2 (APOBEC2)

Function

• C to U editing enzyme, physiological substrate unknown
• no detectable apoB mRNA editing
• low intrinsic cytidine deaminase activity

Cofactor: Zn+2

Structure

• belongs to the cytidine & deoxycytidylate deaminase family

Expression

expressed exclusively in heart & skeletal muscle

More general terms

• DNA dC->dU-editing enzyme (phorbolin)

Database

• OMIM: https://mirror.omim.org/entry/604797
• UniProt: http://www.uniprot.org/uniprot/Q9Y235.html