early-onset Alzheimer's disease
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Etiology
Clinical manifestations
- 38% of cases may present without memory impairment
- may present with behavioral, executive function, visuospatial, or language problems[1]
Laboratory
Radiology
Notes
- neuroimaging takes precedence over lumbar puncture or genetic testing[2]
More general terms
Additional terms
References
- ↑ 1.0 1.1 Balasa M et al Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease Neurology May 17, 2011 76:1720-1725 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/21576687 <Internet> http://www.neurology.org/content/76/20/1720.abstract
- ↑ 2.0 2.1 N Engl J Med Knowledge+ Question of the Week. March 17, 2015
Mayeux R. Clinical practice. Early Alzheimer's disease. N Engl J Med 2010 Jun 19; 362:2194. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20558370
Knopman DS et al. Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2001 May 9; 56:1143 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11342678 - ↑ 3.0 3.1 ARUP Consult: Early-Onset Alzheimer's Panel, Sequencing https://arupconsult.com/ati/early-onset-alzheimers-panel-sequencing