familial Alzheimer's disease (FAD)

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Pathology

  • pathology begins > 20 years before clinical symptoms develop[2]

Genetics

Clinical manifestations

Laboratory

More general terms

More specific terms

Additional terms

References

  1. 1.0 1.1 Balasa M et al Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease Neurology May 17, 2011 76:1720-1725 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/21576687 <Internet> http://www.neurology.org/content/76/20/1720.abstract
  2. 2.0 2.1 Bateman RJ et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 2012 Jul 12 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22784036 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1202753