killer cell lectin-like receptor subfamily F member 2; lectin-like receptor F2; activating coreceptor NKp65 (KLRF2)

Function

• C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity & cytokine secretion in keratinocytes via its interaction with CLEC2A
• interacts with CLEC2A

Structure

• N-glycosylated
• homodimer; non disulfide-linked
• contains 1 C-type lectin domain

Compartment

• cell membrane; single-pass type 2 membrane protein

More general terms

• receptor
• glycoprotein
• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=100431
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:100431
• UniProt: http://www.uniprot.org/uniprot/D3W0D1.html