mumps virus vaccine

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Introduction

Generally used in combination with other vaccines

Pathology

  • no evidence of emergence of resistant genotypes

Management

  • a 3rd vaccine dose around 18 years of age, with or without regular dosing in adulthood is suggested

Notes

  • vaccine protection seems to last an average of 27 years after the last dose (from mathematical models of outbreaks)
  • among people with an immune response to the vaccine, 25% may lose protection by 8 years, 50% by 19 years, & 75% by 38 years (not clear if this is disappearingcirculating IgG or mathematical models of outbreaks)

More general terms

Additional terms

Component of

References

  1. Lewnard JA, Grad YH Vaccine waning and mumps re-emergence in the United States. Sci Transl Med. 2018 Mar 21;10(433) Vol. 10, Issue 433, eaao5945 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29563321 <Internet> http://stm.sciencemag.org/content/10/433/eaao5945