polymixin-B/trimethoprim (Polytrim)

Indications

• eye infections
  • superficial ocular conjunctivitis
  • blepharoconjunctivitis

Contraindications

pregnancy-category C

safety in lactation ?

Dosage

Ophthalmic agent:

• 1 drop every 3 hours up to 6 drops/day

Polymixin B 10,000 units + trimethoprim 1 mg/mL (10 mL).

Adverse effects

• not common (1-10%)
  • burning, stinging, itching, increased redness

More general terms

• antibiotic combination

Components

• polymixin B (Aerosporin)
• trimethoprim; TMP (Proloprim, Trimpex)