poliovirus vaccine

Indications

• immunization against poliovirus

Notes

• wild poliovirus cases have declined by >99.9%, from ~350,000 cases/year to 74 cases in 2 countries in 2015
• decline primarily via use of trivalent oral poliovirus vaccine
• poliovirus vaccine inactivated may have replaced poliovirus vaccine live as the poliovirus vaccine of choice*
• since 2000, the inactivated polio vaccine (IPV) has been exclusively used in the U.S.
• both the live & inactivated vaccines immunize against all three poliovirus types

* it is difficult to envision that financial incentive does not play a role in this choice since the parenteral vaccine requires 4 doses & the oral form 1.

More general terms

• vaccine

More specific terms

• polio virus vaccine, inactivated (IPOL, IPV, Poliovax, Salk vaccine)
• polio virus vaccine,live, trivalent, oral (Orimune, OPV, Sabin vaccine, TOPV)