postpartum hemolytic uremic syndrome (HUS)

Introduction

Also postpartum acute renal failure.

Etiology

retained placenta?

Epidemiology

rare

Clinical manifestations

• occurs days to 10 weeks postpartum, generally 3-6 weeks
• oliguria
• severe hypertension

Laboratory

• CBC with peripheral smear
  • microangiopathic hemolytic anemia
  • thrombocytopenia
• renal function tests
  • oliguria
  • uremia

Management

• dilatation & curettage
• supportive therapy
• fresh frozen plasma
• anti-platelet therapy?
• plasma exchange has been used
• renal failure often persists in survivors

More general terms

• hemolytic uremic syndrome (HUS)
• complications of the puerperium