reactive perforating collagenosis

Etiology

• inflammatory or malignant systemic diseases may coexist with acquired reactive perforating collagenosis

Pathology

• focal hyperkeratosis in direct contact with transepidermal perforating dermal collagen

Clinical manifestations

• umbilicated hyperkeratotic papules or nodules

Management

• topical treatments
• ultraviolet B phototherapy
• oral allopurinol

More general terms

• skin disease (dermatologic disorder, dermatopathy, dermatosis)