sex hormone-binding globulin (SHBG) in serum

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Reference interval

Clinical significance

Increases

Decreases

Notes

  • lower serum SHBG associated with modest reduction in all-cause mortality (RR=0.83-0.94)[11]

More general terms

Additional terms

References

  1. Interpretation of Diagnostic tests, 8th edition, Wallach J, Lippincott, Williams & Wilkens, Philadelphia, 2007, pg 17
  2. Clinical Guide to Laboratory Tests, 4th edition, HB Wu ed, WB Saunders, Philadelphia, 2006
  3. Panel of 5 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0070102.jsp
  4. Panel of 4 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0070109.jsp
  5. Panel of 3 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0070111.jsp
  6. Panel of 3 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0081056.jsp
  7. Panel of 3 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0081057.jsp
  8. Mini Panel of 2 tests: Sex Hormone Binding Globulin 1 . Testosterone, Free LC-MS/MS Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0081059.jsp
  9. Sex Hormone Binding Globulin Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0099375.jsp
  10. Panel of 5 tests Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0000000.jsp
  11. 11.0 11.1 Yeap BB, Marriot RJ, Dwivedi G et al Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men: Individual Participant Data Meta-analyses. Ann Intern Med 2024. May 14. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38739921 Review. https://www.acpjournals.org/doi/10.7326/M23-2781
  12. 12.0 12.1 Grahnemo L, Marriott RJ, Murray K et al Associations of Serum Testosterone and Sex Hormone-Binding Globulin with Incident Fractures in Middle-Aged to Older Men. J Clin Endocrinol Metab. 2024 Oct 7:dgae703. PMID: https://www.ncbi.nlm.nih.gov/pubmed/39373573 https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae703/7814739

Patient information

sex hormone binding globulin (SHBG) in serum patient information