S100A8/A9 in serum (calprotectin in serum)
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Indications
- diagnosis of acute appendicitis (investigational)
Reference interval
- < 20 unit (appendicitis > 20 units)
Clinical significance
- sensitivity 93%, specificity 54% for appendicitis
- negative predictive value of 96%
- positive predictive value of 37%
Increases
- acute appendicitis
More general terms
Additional terms
- calprotectin complex (S100A8/A9)
- protein S100-A8
- protein S100-A9; S100 Ca+2-binding protein A9; calgranulin-B; migration inhibitory factor-related protein 14; MRP-14; p14; Leukocyte L1 complex heavy chain; calprotectin L1H subunit (S100A9, CAGB, CFAG, MRP14)
References
- ↑ Bealer JF and Colgin M. S100A8/A9: A potential new diagnostic aid for acute appendicitis. Acad Emerg Med 2010 Mar; 17:333 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20370768