milk thistle
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Uses
- treatment of hepatitis
* limited evidence it might be helpful for liver disease[1]; does not appear to be effective[2]
Adverse effects
- milk thistle alone doesn't seem harmful[1]
- myalgias[2]
- abnormal liver function tests[2]
- nausea, indigestion, diarrhea[2] Drug effect:
- may interact with medications metabolized by CYP2C9
Drug interactions
- may interfere with metabolism of drugs metabolized by CYP3A4 & CYP2C9
More general terms
Component of
References
- ↑ 1.0 1.1 1.2 Prescriber's Letter 17(2): 2010 Colon and Liver Detoxification Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=260211&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 2.0 2.1 2.2 2.3 2.4 Medical Knowledge Self Assessment Program (MKSAP) 17, 18, 19. American College of Physicians, Philadelphia 2015. 2018, 2022