familial dysalbuminemic hyperthyroxinemia

Etiology

• increase affinity of albumin for thyroxine (T4)

Epidemiology

• most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population

Genetics

• associated with defects in albumin

Clinical manifestations

• persons are euthyroid

Laboratory

• serum thyroxine is increased
• free T4 is normal or increased
• serum TSH should be low to normal

More general terms

• euthyroid hyperthyroxinemia
• inborn error of metabolism

Database

• OMIM: https://mirror.omim.org/entry/103600