hamartomatous polyposis syndrome; familial hamartomatous polyposis

Classification

• juvenile polyposis syndrome
• Peutz-Jeghers syndrome
• PTEN hamartoma tumor syndrome
  • Cowden's disease
  • Bannayan-Zonana syndrome

Pathology

• hamartomatous polyps of the gastrointestinal tract

Genetics

• autosomal-dominant pattern of inheritance

Complications

• increased risk for multiple cancers, including colon cancer

Management

• surveillance & genetic counseling

More general terms

• intestinal polyposis syndrome

More specific terms

• Cowden's disease; multiple hamartoma syndrome including Lhermitte-Duclos disease (cerebelloparenchymal disorder)
• juvenile polyposis coli
• Peutz-Jeghers syndrome (hamartomatous intestinal polyposis)
• PTEN hamartoma tumor syndrome

Additional terms

• hamartoma