myosin 7b (MYO7B)

Function

• myosins are actin-based motor molecules with ATPase activity
• their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments
• may have a role in the apical membranes of transporting epithelia (putative)

Structure

• contains 2 FERM domains
• contains 6 IQ domains
• contains 1 myosin head-like domain
• contains 3 MyTH4 domains
• contains 2 SH3 domains

Compartment

apical cell membrane (putative)

Alternative splicing

named isoforms=2

More general terms

• unconventional myosin

Additional terms

• myosin heavy chain 7B, cardiac muscle beta isoform; myosin cardiac muscle beta chain; antigen MLAA-21; Slow A MYH14 (MYH7B, KIAA1512)

Database

• OMIM: https://mirror.omim.org/entry/606541
• UniProt: http://www.uniprot.org/uniprot/Q6PIF6.html