solute carrier family 15 member 4 (peptide transporter 4, peptide/histidine transporter 1, hPHT1, SLC15A4, PHT1, PTR4, FP12591)

Function

• proton oligopeptide cotransporter
• transports free histidine & certain di- & tripeptides

Structure

• belongs to the PTR2/POT transporter (TC 2.A.17) family

Compartment

membrane (putative)

Alternative splicing

named isoforms=2

Expression

• expressed in skeletal muscle > kidney, liver, & heart > colon & brain
• expressed in low levels throughout the gastrointestinal tract & in Caco-2 cells
• expressed in retinal fragment epithelium (RPE) & neural retina
• expressed in small intestine, stomach, duodenum, jejunum, ileum & colon

More general terms

• solute carrier family 15 (SLC15, SLC15A)
• membrane protein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1212
• UniProt: http://www.uniprot.org/uniprot/Q8N697.html