ribulose-phosphate 3-epimerase; ribulose-5-phosphate-3-epimerase (RPE, HUSSY-17)

Function

• catalyzes reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate

D-ribulose 5-phosphate = D-xylulose 5- phosphate

Cofactor:

• binds 1 divalent metal cation per subunit
• contains tightly bound Fe+2 when produced in E.coli, but the physiological cofactor may be Co+2, Mn+2 or Zn+2

Structure

• homodimer
• belongs to the ribulose-phosphate 3-epimerase family

Alternative splicing

named isoforms=2

More general terms

• epimerase

Additional terms

• HUSSY protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6120
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6120
• OMIM: https://mirror.omim.org/entry/180480
• UniProt: http://www.uniprot.org/uniprot/Q96AT9.html