staphylocoagulase (clumping factor)
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Introduction
Staphylococcus aureus is distinguished from other Staphylococci by the production of coagulase.
2 antigenically distinct forms[2]
- cell-wall bound
- free
Plasma factor may induce release of cell-wall bound coagulase
Coagulase-thrombin complex forms & cleaves fibrinogen to form fibrin clot.