kidney donation

^[1]^[2]^[3]^[4]^[5]

Indications

living kidney donors have survival similar to that of nondonors
risk of end-stage renal disease (ESRD) is not increased
kidney from older donor more likely to result in transplantation rejection than from younger donor^[2]
risk of mortality or cardiovascular events not increased among living kidney donors^[3]
- < 0.01% of kidney donors die within 3 months of surgery^[4]

unilateral nephrectomy for donation of healthy kidney
donation of kidney after circulatory death following withdrawal of life-sustaining treatment
- minimum wait time of 3 hours safe^[5]

↑ Ibrahim HN et al, Long-Term Consequences of Kidney Donation N Engl J Med Volume 360:459-469 January 29, 2009 http://content.nejm.org/cgi/content/short/360/5/459
↑ ^{Jump up to: 2.0} ^2.1 de Fijter JW The impact of age on rejection in kidney transplantation. Drugs Aging. 2005;22(5):433-49. Review PMID: https://www.ncbi.nlm.nih.gov/pubmed/15903355
↑ ^{Jump up to: 3.0} ^3.1 Garg AX et al. Cardiovascular disease in kidney donors: Matched cohort study. BMJ 2012 Mar 1; 344:e1203. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22381674
↑ ^{Jump up to: 4.0} ^4.1 AMA Morning Rounds. August 29, 2024 American Medical Association
Neergaard L Donating a kidney is even safer now than long thought, US study shows. AP Health. August 28, 2024 https://apnews.com/article/kidney-transplant-living-donor-54f6017f04f92f9bfef52ab13155511a#
↑ ^{Jump up to: 5.0} ^5.1 Tingle SJ, Chung NDH, Malik AK et al Donor Time to Death and Kidney Transplant Outcomes in the Setting of a 3-Hour Minimum Wait Policy. JAMA Netw Open. 2024 Nov 4;7(11):e2443353. PMID: https://www.ncbi.nlm.nih.gov/pubmed/39541122 PMCID: PMC11565268 Free PMC article. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2826175