Laron dwarfism; pituitary dwarfism 2; Laron-type pituitary dwarfism 1 (LTD1); Laron syndrome (LS)

Genetics

• associated with defects in GHR

Clinical manifestations

• most severe form of growth hormone insensitivity
• growth impairment
• dysmorphic facial features
• truncal obesity

Laboratory

• levels of GHBP are low or undetectable

More general terms

• dwarfism (nanism)

Database

• OMIM: https://mirror.omim.org/entry/262500